8V82

Alpha7-nicotinic acetylcholine receptor bound to epibatidine and PNU-120596

8V82 の概要

• エントリーDOI: 10.2210/pdb8v82/pdb
• 関連するPDBエントリー: 8UT1 8UTB 8UZJ 8V80 8V86 8V88 8V89 8V8A 8V8C 8V8D
• EMDBエントリー: 43015
• 分子名称: Neuronal acetylcholine receptor subunit alpha-7,Soluble cytochrome b562, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (10 entities in total)
• 機能のキーワード: ion channel, membrane protein, nicotinic receptor
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 359192.34

構造登録者

Burke, S.M.,Noviello, C.M.,Hibbs, R.E. (登録日: 2023-12-04, 公開日: 2024-02-21, 最終更新日: 2024-03-13)

• 主引用文献: Burke, S.M.,Avstrikova, M.,Noviello, C.M.,Mukhtasimova, N.,Changeux, J.P.,Thakur, G.A.,Sine, S.M.,Cecchini, M.,Hibbs, R.E.; Structural mechanisms of alpha 7 nicotinic receptor allosteric modulation and activation.; Cell, 187:1160-1176.e21, 2024; PubMed: 38382524; DOI: 10.1016/j.cell.2024.01.032

実験手法

ELECTRON MICROSCOPY (2.61 Å)