8V6R

Crystal structure of EcThsA in complex with ADPR

8V6R の概要

• エントリーDOI: 10.2210/pdb8v6r/pdb
• 分子名称: Thoeris protein ThsA Macro domain-containing protein, [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE (3 entities in total)
• 機能のキーワード: antiphage immunity, nucleotide signalling, immune system
• 由来する生物種: Escherichia coli
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 56733.63

構造登録者

Shi, Y.,Masic, V.,Mosaiab, T.,Goulart, C.C.,Hartley-Tassell, L.,Sorbello, M.,Vasquez, E.,Mishra, B.P.,Holt, S.,Gu, W.,Kobe, B.,Ve, T. (登録日: 2023-12-02, 公開日: 2024-06-12, 最終更新日: 2024-07-10)

• 主引用文献: Shi, Y.,Masic, V.,Mosaiab, T.,Rajaratman, P.,Hartley-Tassell, L.,Sorbello, M.,Goulart, C.C.,Vasquez, E.,Mishra, B.P.,Holt, S.,Gu, W.,Kobe, B.,Ve, T.; Structural characterization of macro domain-containing Thoeris antiphage defense systems.; Sci Adv, 10:eadn3310-eadn3310, 2024; PubMed: 38924412; DOI: 10.1126/sciadv.adn3310

実験手法

X-RAY DIFFRACTION (2.14 Å)