8V5P

Crystal Structure of the C-terminal domain of the VZV gE ectodomain in complex with the Fab of human antibody 5A2

Summary for 8V5P

• Entry DOI: 10.2210/pdb8v5p/pdb
• Descriptor: Envelope glycoprotein E, 5A2 Fab heavy chain, 5A2 Fab Light Chain (3 entities in total)
• Functional Keywords: glycoprotein e, varicella, zoster, herpes, virus, antibody, viral protein
• Biological source: Human alphaherpesvirus 3 (Varicella-zoster virus); More
• Total number of polymer chains: 12
• Total formula weight: 306095.55

Authors

Harshbarger, W.,Malito, E. (deposition date: 2023-11-30, release date: 2024-10-09)

• Primary citation: Harshbarger, W.D.,Holzapfel, G.,Seraj, N.,Tian, S.,Chesterman, C.,Fu, Z.,Pan, Y.,Harelson, C.,Peng, D.,Huang, Y.,Chandramouli, S.,Malito, E.,Bottomley, M.J.,Williams, J.; Structures of the Varicella Zoster Virus Glycoprotein E and Epitope Mapping of Vaccine-Elicited Antibodies; Vaccines (Basel), 12:-, 2024; DOI: 10.3390/vaccines12101111

Experimental method

X-RAY DIFFRACTION (4.33 Å)