8V5K

Structure of the Human Respirovirus 3 Fusion Protein Bound to Camelid Nanobodies 4C03 and 4C06

Summary for 8V5K

Entry DOI	10.2210/pdb8v5k/pdb
EMDB information	42983
Descriptor	Fusion glycoprotein F0, Camelid Nanobody 4C03, Camelid Nanobody 4C06, ... (4 entities in total)
Functional Keywords	viral fusion protein, camelid nanobodies, viral glycoprotein, membrane fusion, viral protein, viral protein-immune system complex, viral protein/immune system
Biological source	Human respirovirus 3 More
Total number of polymer chains	9
Total formula weight	245401.09
Authors	Johnson, N.V.,Ramamohan, A.R.,McLellan, J.S. (deposition date: 2023-11-30, release date: 2024-05-22, Last modification date: 2024-07-10)
Primary citation	Johnson, N.V.,van Scherpenzeel, R.C.,Bakkers, M.J.G.,Ramamohan, A.R.,van Overveld, D.,Le, L.,Langedijk, J.P.M.,Kolkman, J.A.,McLellan, J.S. Structural basis for potent neutralization of human respirovirus type 3 by protective single-domain camelid antibodies. Nat Commun, 15:5458-5458, 2024 Cited by PubMed: 38937429 DOI: 10.1038/s41467-024-49757-1 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.6 Å)

Structure validation