8V3P

CCP5 in complex with Glu-P-peptide 2 transition state analog

Summary for 8V3P

• Entry DOI: 10.2210/pdb8v3p/pdb
• Descriptor: Cytosolic carboxypeptidase-like protein 5, Tubulin beta-2A chain, ZINC ION, ... (4 entities in total)
• Functional Keywords: carboxypeptidase, deglutamylation, branch glutamate removal, microtubule, hydrolase
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 61141.76

Authors

Chen, J.,Zehr, E.A.,Gruschus, J.M.,Szyk, A.,Liu, Y.,Tanner, M.E.,Tjandra, N.,Roll-Mecak, A. (deposition date: 2023-11-28, release date: 2024-07-17, Last modification date: 2024-08-07)

• Primary citation: Chen, J.,Zehr, E.A.,Gruschus, J.M.,Szyk, A.,Liu, Y.,Tanner, M.E.,Tjandra, N.,Roll-Mecak, A.; Tubulin code eraser CCP5 binds branch glutamates by substrate deformation.; Nature, 631:905-912, 2024; PubMed: 39020174; DOI: 10.1038/s41586-024-07699-0

Experimental method