8UTU

KIF1A[1-393] P305L mutant AMP-PNP bound one and two heads bound states merged, in complex with a microtubule

Summary for 8UTU

• Entry DOI: 10.2210/pdb8utu/pdb
• EMDB information: 42550
• Descriptor: Kinesin-like protein KIF1A, Tubulin alpha-1B chain, Tubulin beta-2B chain, ... (8 entities in total)
• Functional Keywords: kif1a, kinesin, motility, microtubule, tubulin, motor protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 202635.83

Authors

Benoit, M.P.M.H.,Rao, L.,Asenjo, A.B.,Gennerich, A.,Sosa, H. (deposition date: 2023-10-31, release date: 2024-06-12)

• Primary citation: Benoit, M.P.M.H.,Rao, L.,Asenjo, A.B.,Gennerich, A.,Sosa, H.; Cryo-EM of human KIF1A reveals its mechanism of motility and the effect of its pathogenic variant P305L; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3 Å)