8UTO

KIF1A[1-393] AMP-PNP bound two-heads-bound state in complex with a microtubule - class T2L1

Summary for 8UTO

• Entry DOI: 10.2210/pdb8uto/pdb
• EMDB information: 42544
• Descriptor: Kinesin-like protein KIF1A, Tubulin alpha-1B chain, Tubulin beta-2B chain, ... (8 entities in total)
• Functional Keywords: kif1a, kinesin, motility, microtubule, tubulin, motor protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 7
• Total formula weight: 354463.35

Authors

Benoit, M.P.M.H.,Rao, L.,Asenjo, A.B.,Gennerich, A.,Sosa, H. (deposition date: 2023-10-31, release date: 2024-06-12, Last modification date: 2024-07-31)

• Primary citation: Benoit, M.P.M.H.,Rao, L.,Asenjo, A.B.,Gennerich, A.,Sosa, H.; Cryo-EM unveils kinesin KIF1A's processivity mechanism and the impact of its pathogenic variant P305L.; Nat Commun, 15:5530-5530, 2024; PubMed: 38956021; DOI: 10.1038/s41467-024-48720-4

Experimental method

ELECTRON MICROSCOPY (3.2 Å)