8UT1
Alpha7-nicotinic acetylcholine receptor bound to epibatidine
Summary for 8UT1
Entry DOI | 10.2210/pdb8ut1/pdb |
Related | 8UTB 8UZJ 8V80 8V82 8V86 8V88 8V89 8V8A 8V8C 8V8D |
EMDB information | 42526 |
Descriptor | Neuronal acetylcholine receptor subunit alpha-7,Soluble cytochrome b562 fusion, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (9 entities in total) |
Functional Keywords | ion channel, membrane protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 5 |
Total formula weight | 357633.73 |
Authors | Burke, S.M.,Hibbs, R.E.,Noviello, C.M. (deposition date: 2023-10-30, release date: 2024-02-21, Last modification date: 2024-03-13) |
Primary citation | Burke, S.M.,Avstrikova, M.,Noviello, C.M.,Mukhtasimova, N.,Changeux, J.P.,Thakur, G.A.,Sine, S.M.,Cecchini, M.,Hibbs, R.E. Structural mechanisms of alpha 7 nicotinic receptor allosteric modulation and activation. Cell, 187:1160-1176.e21, 2024 Cited by PubMed: 38382524DOI: 10.1016/j.cell.2024.01.032 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.3 Å) |
Structure validation
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