8UR5

I53_dn5 nanoparticle displaying the trimeric HA heads with heptad domain, TH-1heptad-I53_dn5 (local refinement of TH-1heptad)

8UR5 の概要

• エントリーDOI: 10.2210/pdb8ur5/pdb
• EMDBエントリー: 42482
• 分子名称: Trimer head HA,Hemagglutinin HA1 chain, 2-acetamido-2-deoxy-beta-D-glucopyranose (2 entities in total)
• 機能のキーワード: influenza virus, hemagglutinin nanoparticle vaccine, structural genomics, seattle structural genomics center for infectious disease, ssgcid, viral protein
• 由来する生物種: synthetic construct; 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 135415.11

構造登録者

Park, Y.J.,Veesler, D.,Seattle Structural Genomics Center for Infectious Disease (SSGCID) (登録日: 2023-10-25, 公開日: 2023-12-27)

• 主引用文献: Ellis, D.,Dosey, A.,Boyoglu-Barnum, S.,Park, Y.J.,Gillespie, R.,Syeda, H.,Hutchinson, G.B.,Tsybovsky, Y.,Murphy, M.,Pettie, D.,Matheson, N.,Chan, S.,Ueda, G.,Fallas, J.A.,Carter, L.,Graham, B.S.,Veesler, D.,Kanekiyo, M.,King, N.P.; Antigen spacing on protein nanoparticles influences antibody responses to vaccination.; Cell Rep, 42:113552-113552, 2023; PubMed: 38096058; DOI: 10.1016/j.celrep.2023.113552

実験手法

ELECTRON MICROSCOPY (3.7 Å)