8UFR
Structure of human endothelial nitric oxide synthase heme domain in complex with 4-methyl-7-(4-methyl-2,3,4,5-tetrahydrobenzo[f][1,4]oxazepin-7-yl)quinolin-2-amine dihydrochloride
Summary for 8UFR
Entry DOI | 10.2210/pdb8ufr/pdb |
Descriptor | Nitric oxide synthase, endothelial, PROTOPORPHYRIN IX CONTAINING FE, 5,6,7,8-TETRAHYDROBIOPTERIN, ... (10 entities in total) |
Functional Keywords | nitric oxide synthase inhibitor, heme enzyme, oxidoreductase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 4 |
Total formula weight | 205479.07 |
Authors | Li, H.,Poulos, T.L. (deposition date: 2023-10-04, release date: 2024-03-13, Last modification date: 2024-04-03) |
Primary citation | Li, H.,Hardy, C.D.,Reidl, C.T.,Jing, Q.,Xue, F.,Cinelli, M.,Silverman, R.B.,Poulos, T.L. Crystallographic and Computational Insights into Isoform-Selective Dynamics in Nitric Oxide Synthase. Biochemistry, 63:788-796, 2024 Cited by PubMed: 38417024DOI: 10.1021/acs.biochem.3c00601 PDB entries with the same primary citation |
Experimental method |
Structure validation
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