8U9V

Structure of the SARS-CoV-2 main protease in complex with inhibitor MPI101

8U9V の概要

• エントリーDOI: 10.2210/pdb8u9v/pdb
• 分子名称: 3C-like proteinase nsp5, N-{(2R)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-4-methyl-N~2~-{[(pyridin-3-yl)methoxy]carbonyl}-L-leucinamide, DIMETHYL SULFOXIDE, ... (4 entities in total)
• 機能のキーワード: main protease, viral protein, hydrolase-inhibitor complex, hydrolase/inhibitor
• 由来する生物種: Severe acute respiratory syndrome coronavirus 2
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 34324.18

構造登録者

Blankenship, L.R.,Liu, W.R. (登録日: 2023-09-20, 公開日: 2024-09-25)

• 主引用文献: Blankenship, L.R.,Sankaran, B.,Liu, W.R.; Structure of the SARS-CoV-2 main protease in complex with inhibitors; To Be Published,

実験手法

X-RAY DIFFRACTION (1.65 Å)