8U8V
Cryo-EM structure of Substrate ATP Bound in the Insertion Site (IS) of Human Mitochondrial Transcription Elongation Complex
Summary for 8U8V
Entry DOI | 10.2210/pdb8u8v/pdb |
EMDB information | 42028 |
Descriptor | Transcription elongation factor, mitochondrial, DNA-directed RNA polymerase, mitochondrial, Non-Template Strand DNA (NT27mt), ... (7 entities in total) |
Functional Keywords | mitochondrial rna polymerase, nucleotide selection, nucleotide discrimination, transcription, protein-rna-dna complex, polrmt, tefm, transcription-dna-rna complex, transcription/dna/rna |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 6 |
Total formula weight | 207601.52 |
Authors | |
Primary citation | Herbine, K.,Nayak, A.R.,Temiakov, D. Structural basis for substrate binding and selection by human mitochondrial RNA polymerase. Nat Commun, 15:7134-7134, 2024 Cited by PubMed: 39164235DOI: 10.1038/s41467-024-50817-9 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.74 Å) |
Structure validation
Download full validation report