8U8V

Cryo-EM structure of Substrate ATP Bound in the Insertion Site (IS) of Human Mitochondrial Transcription Elongation Complex

8U8V の概要

• エントリーDOI: 10.2210/pdb8u8v/pdb
• EMDBエントリー: 42028
• 分子名称: Transcription elongation factor, mitochondrial, DNA-directed RNA polymerase, mitochondrial, Non-Template Strand DNA (NT27mt), ... (7 entities in total)
• 機能のキーワード: mitochondrial rna polymerase, nucleotide selection, nucleotide discrimination, transcription, protein-rna-dna complex, polrmt, tefm, transcription-dna-rna complex, transcription/dna/rna
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 207601.52

構造登録者

Herbine, K.H.,Nayak, A.R.,Temiakov, D. (登録日: 2023-09-18, 公開日: 2024-09-04)

• 主引用文献: Herbine, K.,Nayak, A.R.,Temiakov, D.; Structural basis for substrate binding and selection by human mitochondrial RNA polymerase.; Nat Commun, 15:7134-7134, 2024; PubMed: 39164235; DOI: 10.1038/s41467-024-50817-9

実験手法

ELECTRON MICROSCOPY (2.74 Å)