8U5L

MAU868, a novel human-derived monoclonal neutralizing antibody targeting BK virus VP1

Summary for 8U5L

• Entry DOI: 10.2210/pdb8u5l/pdb
• Descriptor: Capsid protein VP1, scFv fragment of the monoclonal antibody MAU868 (3 entities in total)
• Functional Keywords: antibody fragment, scfv, viral protein-immune system complex, viral protein/immune system
• Biological source: Betapolyomavirus hominis; More
• Total number of polymer chains: 10
• Total formula weight: 281683.76

Authors

Knapp, M.S.,Ornelas, E. (deposition date: 2023-09-12, release date: 2024-08-14)

• Primary citation: Abend, J.R.,Sathe, A.,Wrobel, M.B.,Knapp, M.,Xu, L.,Zhao, L.,Kim, P.,Desai, S.,Nguyen, A.,Leber, X.C.,Hein, A.,Scharenberg, M.,Shaul, J.,Ornelas, E.,Wong, K.,Pietzonka, T.,Sterling, L.M.,Hodges, M.R.,Pertel, P.,Traggiai, E.,Patick, A.K.,Kovacs, S.J.; Nonclinical and clinical characterization of MAU868, a novel human-derived monoclonal neutralizing antibody targeting BK polyomavirus VP1.; Am J Transplant, 2024; PubMed: 38996969; DOI: 10.1016/j.ajt.2024.07.002

Experimental method