8U58

The mTORC1 cholesterol sensor LYCHOS (GPR155) with tryptophan

Summary for 8U58

Entry DOI	10.2210/pdb8u58/pdb
EMDB information	41912 41913 41914
Descriptor	Integral membrane protein GPR155, 2-acetamido-2-deoxy-beta-D-glucopyranose (2 entities in total)
Functional Keywords	pin-formed, gpcr, cholesterol, auxin, transporter, cell-growth, mtorc1, cancer, membrane protein
Biological source	Homo sapiens (human)
Total number of polymer chains	2
Total formula weight	198996.20
Authors	Bayly-Jones, C.,Lupton, C.J.,Ellisdon, A.M. (deposition date: 2023-09-12, release date: 2024-09-18)
Primary citation	Bayly-Jones, C.,Lupton, C.J.,Chang, Y.G.,Keen, A.C.,Jones, G.D.,Venugopal, H.,Halls, M.L.,Ellisdon, A.M. The structure of GPR155 To Be Published,
Experimental method	ELECTRON MICROSCOPY (2.45 Å)

Structure validation