8U57
PPARg LBD in complex with perfluorooctanoic acid (PFOA)
Summary for 8U57
| Entry DOI | 10.2210/pdb8u57/pdb |
| Descriptor | Peroxisome proliferator-activated receptor gamma, pentadecafluorooctanoic acid, (4S,5S)-1,2-DITHIANE-4,5-DIOL, ... (4 entities in total) |
| Functional Keywords | nuclear receptor ligand-binding domain, nuclear protein |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 1 |
| Total formula weight | 35125.03 |
| Authors | Pederick, J.L.,Frkic, R.L.,McDougal, D.P.,Bruning, J.B. (deposition date: 2023-09-12, release date: 2024-07-24) |
| Primary citation | Pederick, J.L.,Frkic, R.L.,McDougal, D.P.,Bruning, J.B. A structural basis for the activation of peroxisome proliferator-activated receptor gamma (PPAR gamma ) by perfluorooctanoic acid (PFOA). Chemosphere, 354:141723-141723, 2024 Cited by PubMed: 38494006DOI: 10.1016/j.chemosphere.2024.141723 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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