8U57

PPARg LBD in complex with perfluorooctanoic acid (PFOA)

8U57 の概要

• エントリーDOI: 10.2210/pdb8u57/pdb
• 分子名称: Peroxisome proliferator-activated receptor gamma, pentadecafluorooctanoic acid, (4S,5S)-1,2-DITHIANE-4,5-DIOL, ... (4 entities in total)
• 機能のキーワード: nuclear receptor ligand-binding domain, nuclear protein
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 35125.03

構造登録者

Pederick, J.L.,Frkic, R.L.,McDougal, D.P.,Bruning, J.B. (登録日: 2023-09-12, 公開日: 2024-07-24)

• 主引用文献: Pederick, J.L.,Frkic, R.L.,McDougal, D.P.,Bruning, J.B.; A structural basis for the activation of peroxisome proliferator-activated receptor gamma (PPAR gamma ) by perfluorooctanoic acid (PFOA).; Chemosphere, 354:141723-141723, 2024; PubMed: 38494006; DOI: 10.1016/j.chemosphere.2024.141723

実験手法

X-RAY DIFFRACTION (2 Å)