8U26

Gaussian Mixture Models based single particle refinement - GPCR (Substance P bound to active human neurokinin 1 receptor in complex with miniGs399 from EMPIAR-10786)

8U26 の概要

• エントリーDOI: 10.2210/pdb8u26/pdb
• EMDBエントリー: 24570 41840
• 分子名称: Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (6 entities in total)
• 機能のキーワード: gpcr, membrane protein
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 141549.56

構造登録者

Chen, M.,Pintilie, G. (登録日: 2023-09-05, 公開日: 2023-11-15, 最終更新日: 2024-01-24)

• 主引用文献: Chen, M.,Schmid, M.F.,Chiu, W.; Improving resolution and resolvability of single-particle cryoEM structures using Gaussian mixture models.; Nat.Methods, 21:37-40, 2024; PubMed: 37973972; DOI: 10.1038/s41592-023-02082-9

実験手法

ELECTRON MICROSCOPY (2.5 Å)