8U0N

Crystal structure of isopentenyl phosphate kinase from Thermococcus paralvinellae bound to 2-cyclopentylideneethyl monophosphate and ADP

Summary for 8U0N

Entry DOI	10.2210/pdb8u0n/pdb
Descriptor	Isopentenyl phosphate kinase, ADENOSINE-5'-DIPHOSPHATE, 2-cyclopentylideneethyl dihydrogen phosphate, ... (4 entities in total)
Functional Keywords	alternate mevalonate pathway ipk amino acid kinase isoprenoids, transferase
Biological source	Thermococcus paralvinellae
Total number of polymer chains	2
Total formula weight	65164.41
Authors	Singh, S.,Thomas, L.M.,Johnson, B.P.,Brown, S. (deposition date: 2023-08-29, release date: 2024-02-21, Last modification date: 2024-06-12)
Primary citation	Johnson, B.P.,Mandal, P.S.,Brown, S.M.,Thomas, L.M.,Singh, S. Ternary complexes of isopentenyl phosphate kinase from Thermococcus paralvinellae reveal molecular determinants of non-natural substrate specificity. Proteins, 92:808-818, 2024 Cited by PubMed: 38333996 DOI: 10.1002/prot.26674 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation