8TXO

E. coli DNA-directed RNA polymerase transcription elongation complex bound to the unnatural dZ-PTP base pair in the active site

8TXO の概要

• エントリーDOI: 10.2210/pdb8txo/pdb
• EMDBエントリー: 41695
• 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... (9 entities in total)
• 機能のキーワード: complex, unnatural base pairs, synthetic biology, transcription
• 由来する生物種: Escherichia coli; 詳細
• タンパク質・核酸の鎖数: 7
• 化学式量合計: 397457.61

構造登録者

Aiyer, S.,Shan, Z.,Oh, J.,Wang, D.,Tan, Y.Z.,Lyumkis, D. (登録日: 2023-08-23, 公開日: 2024-01-24)

• 主引用文献: Aiyer, S.,Baldwin, P.R.,Tan, S.M.,Shan, Z.,Oh, J.,Mehrani, A.,Bowman, M.E.,Louie, G.,Passos, D.O.,Dordevic-Marquardt, S.,Mietzsch, M.,Hull, J.A.,Hoshika, S.,Barad, B.A.,Grotjahn, D.A.,McKenna, R.,Agbandje-McKenna, M.,Benner, S.A.,Noel, J.A.P.,Wang, D.,Tan, Y.Z.,Lyumkis, D.; Overcoming resolution attenuation during tilted cryo-EM data collection.; Nat Commun, 15:389-389, 2024; PubMed: 38195598; DOI: 10.1038/s41467-023-44555-7

実験手法

ELECTRON MICROSCOPY (3.1 Å)