8TWW
Crystal structure of nitrile synthase AetD with substrate bound and cofactor fully assembled
Summary for 8TWW
Entry DOI | 10.2210/pdb8tww/pdb |
Related | 8TWN 8TWT |
Descriptor | AetD, (2S)-2-azanyl-3-[5,7-bis(bromanyl)-1H-indol-3-yl]propanoic acid, FE (III) ION, ... (4 entities in total) |
Functional Keywords | nitrile synthase, non-heme iron enzyme, diiron enzyme, oxidoreductase |
Biological source | Aetokthonos hydrillicola |
Total number of polymer chains | 2 |
Total formula weight | 62284.71 |
Authors | Ye, N.,Drennan, C.L. (deposition date: 2023-08-21, release date: 2024-08-28, Last modification date: 2024-10-16) |
Primary citation | Adak, S.,Ye, N.,Calderone, L.A.,Duan, M.,Lubeck, W.,Schafer, R.J.B.,Lukowski, A.L.,Houk, K.N.,Pandelia, M.E.,Drennan, C.L.,Moore, B.S. A single diiron enzyme catalyses the oxidative rearrangement of tryptophan to indole nitrile. Nat.Chem., 2024 Cited by PubMed: 39285206DOI: 10.1038/s41557-024-01603-z PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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