8TPS
nhTMEM16 A444P mutant in lipid nanodiscs with MSP1E3 scaffold protein in the presence of Ca2+ (bent TM6)
Summary for 8TPS
Entry DOI | 10.2210/pdb8tps/pdb |
EMDB information | 41483 |
Descriptor | Lipid scramblase nhTMEM16, CALCIUM ION, (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate (3 entities in total) |
Functional Keywords | membrane protein, lipid scramblase, tmem16, lipid transport |
Biological source | Fusarium vanettenii 77-13-4 |
Total number of polymer chains | 2 |
Total formula weight | 169716.37 |
Authors | |
Primary citation | Feng, Z.,Alvarenga, O.E.,Accardi, A. Structural basis of closed groove scrambling by a TMEM16 protein. Nat.Struct.Mol.Biol., 2024 Cited by PubMed: 38684930DOI: 10.1038/s41594-024-01284-9 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.97 Å) |
Structure validation
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