8TOU
ACE2-peptide 2 complex crystal form 3
Summary for 8TOU
Entry DOI | 10.2210/pdb8tou/pdb |
Related | 8TOQ 8TOR 8TOS 8TOT |
Descriptor | Angiotensin-converting enzyme 2, Cyclic peptide 2, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total) |
Functional Keywords | peptidase, enzyme, sars-cov-2, angiotensin, protein binding |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 75509.36 |
Authors | |
Primary citation | Bedding, M.J.,Franck, C.,Johansen-Leete, J.,Aggarwal, A.,Maxwell, J.W.C.,Patel, K.,Hawkins, P.M.E.,Low, J.K.K.,Siddiquee, R.,Sani, H.M.,Ford, D.J.,Turville, S.,Mackay, J.P.,Passioura, T.,Christie, M.,Payne, R.J. Discovery of High Affinity Cyclic Peptide Ligands for Human ACE2 with SARS-CoV-2 Entry Inhibitory Activity. Acs Chem.Biol., 19:141-152, 2024 Cited by PubMed: 38085789DOI: 10.1021/acschembio.3c00568 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.1 Å) |
Structure validation
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