8TNT

Crystal structure of Epstein-Barr virus gH/gL/gp42 in complex with antibodies F-2-1 and 769C2

8TNT の概要

• エントリーDOI: 10.2210/pdb8tnt/pdb
• 分子名称: Envelope glycoprotein H, Envelope glycoprotein L, Glycoprotein 42, ... (8 entities in total)
• 機能のキーワード: viral protein, antibody, immune system
• 由来する生物種: Epstein-Barr virus; 詳細
• タンパク質・核酸の鎖数: 7
• 化学式量合計: 203227.55

構造登録者

Bu, W.,Kumar, A.,Board, N.,Kim, J.,Dowdell, K.,Zhang, S.,Lei, Y.,Hostal, A.,Krogmann, T.,Wang, Y.,Pittaluga, S.,Marcotrigiano, J.,Cohen, J.I. (登録日: 2023-08-02, 公開日: 2024-03-27)

• 主引用文献: Bu, W.,Kumar, A.,Board, N.L.,Kim, J.,Dowdell, K.,Zhang, S.,Lei, Y.,Hostal, A.,Krogmann, T.,Wang, Y.,Pittaluga, S.,Marcotrigiano, J.,Cohen, J.I.; Epstein-Barr virus gp42 antibodies reveal sites of vulnerability for receptor binding and fusion to B cells.; Immunity, 57:559-573.e6, 2024; PubMed: 38479361; DOI: 10.1016/j.immuni.2024.02.008

実験手法

X-RAY DIFFRACTION (3.15 Å)