8TLV

Crystal structure of MBP and AF9 AHD fusion protein 4AQK in complex with peptidomimetic inhibitor 28

8TLV の概要

• エントリーDOI: 10.2210/pdb8tlv/pdb
• 関連するBIRD辞書のPRD_ID: PRD_900001
• 分子名称: MBP and AF9 AHD fusion protein 4AQK, peptidomimetic inhibitor 28, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, ... (5 entities in total)
• 機能のキーワード: mll fusion super elongation complex (sec) acute lymphoblastic leukemia acute myeloid leukemia, translation
• 由来する生物種: Escherichia coli K-12; 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 50371.93

構造登録者

Yang, Y.,Nikolovska-Coleska, Z. (登録日: 2023-07-27, 公開日: 2024-05-29)

• 主引用文献: Yang, Y.,Ahmad, E.,Premkumar, V.,Liu, A.,Ashikur Rahman, S.M.,Nikolovska-Coleska, Z.; Structural studies of intrinsically disordered MLL-fusion protein AF9 in complex with peptidomimetic inhibitors.; Protein Sci., 33:e5019-e5019, 2024; PubMed: 38747396; DOI: 10.1002/pro.5019

実験手法

X-RAY DIFFRACTION (2.659 Å)