8TK5

HUMAN VH1-RELATED DUAL-SPECIFICITY PHOSPHATASE (VHR) complexed with HEPES

Summary for 8TK5

• Entry DOI: 10.2210/pdb8tk5/pdb
• Descriptor: Dual specificity protein phosphatase 3, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, TETRAETHYLENE GLYCOL, ... (6 entities in total)
• Functional Keywords: protein dual-specificity phosphatase, vhr, hydrolase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 41819.51

Authors

Aleshin, A.E.,Wu, J.,Lambert, L.J.,Cosford, N.D.P.,Tautz, L. (deposition date: 2023-07-25, release date: 2024-08-14)

• Primary citation: Wu, J.,Aleshin, A.E.,Lambert, L.J.,Cosford, N.D.P.,Tautz, L.; Fragment Screening Platform and Discovery of Novel Fragment Binders of the VHR Phosphatase, a Drug Target for Sepsis and Septic Shock; To Be Published,

Experimental method