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8TK3

HUMAN VH1-RELATED DUAL-SPECIFICITY PHOSPHATASE (VHR) having oxidized catalytic cysteine and complexed with 6-(difluoromethyl)pyrimidin-4-ol at two allosteric sites

Summary for 8TK3
Entry DOI10.2210/pdb8tk3/pdb
DescriptorDual specificity protein phosphatase 3, 6-(difluoromethyl)pyrimidin-4-ol, DIMETHYL SULFOXIDE, ... (4 entities in total)
Functional Keywordsprotein dual-specificity phosphatase, vhr, hydrolase
Biological sourceHomo sapiens (human)
Total number of polymer chains1
Total formula weight20841.59
Authors
Aleshin, A.E.,Wu, J.,Lambert, L.J.,Cosford, N.D.P.,Tautz, L. (deposition date: 2023-07-25, release date: 2024-08-14)
Primary citationAleshin, A.E.,Wu, J.,Lambert, L.J.,Cosford, N.D.P.,Tautz, L.
HUMAN VH1-RELATED DUAL-SPECIFICITY PHOSPHATASE (VHR) having oxidized catalytic cysteine and complexed with 6-(difluoromethyl)pyrimidin-4-ol at two allosteric sites
To Be Published,
Experimental method
Structure validation

223790

數據於2024-08-14公開中

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