8TGU

Cryo-EM structure of BG505 SOSIP trimer purified via Galanthus nivalis lectin chromatography

8TGU の概要

• エントリーDOI: 10.2210/pdb8tgu/pdb
• EMDBエントリー: 41244
• 分子名称: HIV-1 Envelope glycoprotein BG505 SOSIP, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• 機能のキーワード: hiv-1, glycoprotein, lectin, trimer, viral protein
• 由来する生物種: Human immunodeficiency virus 1
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 233006.49

構造登録者

Parsons, R.J.,Pothula, K.,Acharya, P. (登録日: 2023-07-13, 公開日: 2024-08-28, 最終更新日: 2024-09-04)

• 主引用文献: Parthasarathy, D.,Pothula, K.R.,Ratnapriya, S.,Cervera Benet, H.,Parsons, R.,Huang, X.,Sammour, S.,Janowska, K.,Harris, M.,Sodroski, J.,Acharya, P.,Herschhorn, A.; Conformational flexibility of HIV-1 envelope glycoproteins modulates transmitted/founder sensitivity to broadly neutralizing antibodies.; Nat Commun, 15:7334-7334, 2024; PubMed: 39187497; DOI: 10.1038/s41467-024-51656-4

実験手法

ELECTRON MICROSCOPY (3.8 Å)