8TG9

Complex of NPR1 ectodomain with ANP plus an allosteric activating antibody, REGN5381

Summary for 8TG9

• Entry DOI: 10.2210/pdb8tg9/pdb
• EMDB information: 41233
• Descriptor: Atrial natriuretic peptide receptor 1, Atrial natriuretic peptide, REGN5381 Fab heavy chain, ... (8 entities in total)
• Functional Keywords: atrial natriuretic peptide, antibody, activator, pulmonary hypertension, immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 7
• Total formula weight: 206851.01

Authors

Franklin, M.C.,Romero Hernandez, A. (deposition date: 2023-07-12, release date: 2024-07-17)

• Primary citation: Franklin, M.C.,Romero Hernandez, A.; Complex of NPR1 ectodomain with ANP plus an allosteric activating antibody, REGN5381; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.08 Å)