8TG3

tRNA 2'-phosphotransferase (Tpt1) from Aeropyrum pernix in complex with ADP-ribose-1" -phosphate

Summary for 8TG3

• Entry DOI: 10.2210/pdb8tg3/pdb
• Related: 8TFI
• Descriptor: Probable RNA 2'-phosphotransferase, [[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2~{R},3~{S},4~{R},5~{R})-3,4-bis(oxidanyl)-5-phosphonooxy-oxolan-2-yl]methyl hydrogen phosphate, NITRATE ION, ... (7 entities in total)
• Functional Keywords: trna 2'-phosphotransferase, tpt1, trna splicing, adp-ribose-1"-phosphate, aeropyrum pernix, transferase
• Biological source: Aeropyrum pernix
• Total number of polymer chains: 1
• Total formula weight: 24536.74

Authors

Jacewicz, A.,Dantuluri, S.,Shuman, S. (deposition date: 2023-07-12, release date: 2023-11-08)

• Primary citation: Jacewicz, A.,Dantuluri, S.,Shuman, S.; Structural basis for Tpt1-catalyzed 2'-PO 4 transfer from RNA and NADP(H) to NAD.; Proc.Natl.Acad.Sci.USA, 120:e2312999120-e2312999120, 2023; PubMed: 37883434; DOI: 10.1073/pnas.2312999120

Experimental method

X-RAY DIFFRACTION (1.47 Å)