8TFY

tRNA 2'-phosphotransferase (Tpt1) from Pyrococcus horikoshii in complex with NADP

Summary for 8TFY

Entry DOI	10.2210/pdb8tfy/pdb
Related	8TFI
Descriptor	Probable RNA 2'-phosphotransferase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, CHLORIDE ION, ... (4 entities in total)
Functional Keywords	trna 2'-phosphotransferase, tpt1, trna splicing, nadp, nad, transferase
Biological source	Pyrococcus horikoshii OT3
Total number of polymer chains	1
Total formula weight	21653.53
Authors	Jacewicz, A.,Dantuluri, S.,Shuman, S. (deposition date: 2023-07-12, release date: 2023-11-08)
Primary citation	Jacewicz, A.,Dantuluri, S.,Shuman, S. Structural basis for Tpt1-catalyzed 2'-PO 4 transfer from RNA and NADP(H) to NAD. Proc.Natl.Acad.Sci.USA, 120:e2312999120-e2312999120, 2023 Cited by PubMed: 37883434 DOI: 10.1073/pnas.2312999120 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.54 Å)

Structure validation