8TFR

Apo Fab from C10-S66K antibody

8TFR の概要

• エントリーDOI: 10.2210/pdb8tfr/pdb
• 分子名称: Immunoglobulin G-binding protein G, Heavy chain from Fab of C10_S66K antibody, Light chain from Fab of C10_S66K antibody (3 entities in total)
• 機能のキーワード: antibody, fentanyl analogue, carfentanil, opioid, immune system
• 由来する生物種: Streptococcus sp. group G; 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 53987.10

構造登録者

Pholcharee, T.,Wilson, I.A. (登録日: 2023-07-11, 公開日: 2023-08-16, 最終更新日: 2023-08-23)

• 主引用文献: Eubanks, L.M.,Pholcharee, T.,Oyen, D.,Natori, Y.,Zhou, B.,Wilson, I.A.,Janda, K.D.; An Engineered Human-Antibody Fragment with Fentanyl Pan-Specificity That Reverses Carfentanil-Induced Respiratory Depression.; Acs Chem Neurosci, 14:2849-2856, 2023; PubMed: 37534714; DOI: 10.1021/acschemneuro.3c00455

実験手法

X-RAY DIFFRACTION (2.99 Å)