8TFQ

Fab from C10-S66K antibody in complex with fentanyl

8TFQ の概要

• エントリーDOI: 10.2210/pdb8tfq/pdb
• 分子名称: Light chain from Fab of C10_S66K antibody, Heavy chain from Fab of C10_S66K antibody, N-phenyl-N-[1-(2-phenylethyl)piperidin-4-yl]propanamide, ... (4 entities in total)
• 機能のキーワード: antibody, fentanyl, opioid., immune system
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 94133.41

構造登録者

Pholcharee, T.,Wilson, I.A. (登録日: 2023-07-11, 公開日: 2023-08-16, 最終更新日: 2023-08-23)

• 主引用文献: Eubanks, L.M.,Pholcharee, T.,Oyen, D.,Natori, Y.,Zhou, B.,Wilson, I.A.,Janda, K.D.; An Engineered Human-Antibody Fragment with Fentanyl Pan-Specificity That Reverses Carfentanil-Induced Respiratory Depression.; Acs Chem Neurosci, 14:2849-2856, 2023; PubMed: 37534714; DOI: 10.1021/acschemneuro.3c00455

実験手法

X-RAY DIFFRACTION (1.8 Å)