8TFN
Structure of anti-TCRvbeta6-5 antibody in complex with the cognate TCR
Summary for 8TFN
Entry DOI | 10.2210/pdb8tfn/pdb |
Descriptor | TRAV12-3, TRBV6-5, Anti-TCRVb6-5 Fab heavy chain, ... (5 entities in total) |
Functional Keywords | tcr, anti-tcr, trbv12-3, trbv6-5, complex structure, immune system |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 4 |
Total formula weight | 97122.98 |
Authors | Katragadda, M.,Servatalab, R.,Wirth, J. (deposition date: 2023-07-11, release date: 2023-11-08, Last modification date: 2024-05-22) |
Primary citation | Vantourout, P.,Eum, J.,Conde Poole, M.,Hayday, T.S.,Laing, A.G.,Hussain, K.,Nuamah, R.,Kannambath, S.,Moisan, J.,Stoop, A.,Battaglia, S.,Servattalab, R.,Hsu, J.,Bayliffe, A.,Katragadda, M.,Hayday, A.C. Innate TCR beta-chain engagement drives human T cells toward distinct memory-like effector phenotypes with immunotherapeutic potentials. Sci Adv, 9:eadj6174-eadj6174, 2023 Cited by PubMed: 38055824DOI: 10.1126/sciadv.adj6174 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.54 Å) |
Structure validation
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