8TFA

Diphosphoinositol polyphosphate phosphohydrolase 1 (DIPP1/NUDT3) in complex with myo-5-PP-IP4, produced upon myo-(2OH)-IP5 phosphorylation by TvIPK

8TFA の概要

• エントリーDOI: 10.2210/pdb8tfa/pdb
• 分子名称: Diphosphoinositol polyphosphate phosphohydrolase 1, (1r,2R,3S,4r,5R,6S)-4-hydroxy-2,3,5,6-tetrakis(phosphonooxy)cyclohexyl trihydrogen diphosphate, MAGNESIUM ION, ... (6 entities in total)
• 機能のキーワード: inositol phosphate, inositol, phosphatase, nut3, dipp1, hydrolase
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 17902.77

構造登録者

Zong, G.,Wang, H.,Shears, S.B. (登録日: 2023-07-09, 公開日: 2023-11-15, 最終更新日: 2024-02-14)

• 主引用文献: Zong, G.,Desfougeres, Y.,Portela-Torres, P.,Kwon, Y.U.,Saiardi, A.,Shears, S.B.,Wang, H.; Biochemical and structural characterization of an inositol pyrophosphate kinase from a giant virus.; Embo J., 43:462-480, 2024; PubMed: 38216735; DOI: 10.1038/s44318-023-00005-0

実験手法

X-RAY DIFFRACTION (1.4 Å)