8TCI
Crystal structure of DNMT3C-DNMT3L in complex with CGG DNA
Summary for 8TCI
Entry DOI | 10.2210/pdb8tci/pdb |
Descriptor | DNA (cytosine-5)-methyltransferase 3C, DNA (cytosine-5)-methyltransferase 3-like, (5'-D(P*CP*AP*TP*G)-R(P*(PYO))-D(P*GP*GP*TP*CP*TP*AP*AP*TP*TP*AP*GP*AP*CP*CP*GP*CP*AP*TP*G)-3'), ... (4 entities in total) |
Functional Keywords | dna cytosine methyltransferase, transferase |
Biological source | Mus musculus (house mouse) More |
Total number of polymer chains | 6 |
Total formula weight | 126630.16 |
Authors | Khudaverdyan, N.,Song, J. (deposition date: 2023-07-01, release date: 2024-08-14, Last modification date: 2024-09-11) |
Primary citation | Khudaverdyan, N.,Lu, J.,Chen, X.,Herle, G.,Song, J. The structure of DNA methyltransferase DNMT3C reveals an activity-tuning mechanism for DNA methylation. J.Biol.Chem., 300:107633-107633, 2024 Cited by PubMed: 39098534DOI: 10.1016/j.jbc.2024.107633 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.19 Å) |
Structure validation
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