8TCI

Crystal structure of DNMT3C-DNMT3L in complex with CGG DNA

8TCI の概要

• エントリーDOI: 10.2210/pdb8tci/pdb
• 分子名称: DNA (cytosine-5)-methyltransferase 3C, DNA (cytosine-5)-methyltransferase 3-like, (5'-D(P*CP*AP*TP*G)-R(P*(PYO))-D(P*GP*GP*TP*CP*TP*AP*AP*TP*TP*AP*GP*AP*CP*CP*GP*CP*AP*TP*G)-3'), ... (4 entities in total)
• 機能のキーワード: dna cytosine methyltransferase, transferase
• 由来する生物種: Mus musculus (house mouse); 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 126630.16

構造登録者

Khudaverdyan, N.,Song, J. (登録日: 2023-07-01, 公開日: 2024-08-14, 最終更新日: 2024-09-11)

• 主引用文献: Khudaverdyan, N.,Lu, J.,Chen, X.,Herle, G.,Song, J.; The structure of DNA methyltransferase DNMT3C reveals an activity-tuning mechanism for DNA methylation.; J.Biol.Chem., 300:107633-107633, 2024; PubMed: 39098534; DOI: 10.1016/j.jbc.2024.107633

実験手法

X-RAY DIFFRACTION (3.19 Å)