8TAN
CryoEM structure of MFRV-VILP bound to IGF1Rzip
Summary for 8TAN
Entry DOI | 10.2210/pdb8tan/pdb |
EMDB information | 41138 |
Descriptor | Insulin-like growth factor 1 receptor, Insulin-like growth factor, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total) |
Functional Keywords | igf1r, mfrv-vilp, vilp, signaling protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 3 |
Total formula weight | 228542.13 |
Authors | Kirk, N.S. (deposition date: 2023-06-27, release date: 2024-01-17, Last modification date: 2024-01-31) |
Primary citation | Chrudinova, M.,Kirk, N.S.,Chuard, A.,Venugopal, H.,Zhang, F.,Lubos, M.,Gelfanov, V.,Panikova, T.,Zakova, L.,Cutone, J.,Mojares, M.,DiMarchi, R.,Jiracek, J.,Altindis, E. A viral insulin-like peptide inhibits IGF-1 receptor phosphorylation and regulates IGF1R gene expression. Mol Metab, 80:101863-101863, 2024 Cited by PubMed: 38182007DOI: 10.1016/j.molmet.2023.101863 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.05 Å) |
Structure validation
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