8TA1
Crystal Structure of Dihydrofolate reductase (DHFR) from Mycobacterium ulcerans Agy99 in complex with NADP and inhibitor MAM907
Summary for 8TA1
Entry DOI | 10.2210/pdb8ta1/pdb |
Descriptor | Dihydrofolate reductase, SODIUM ION, ACETATE ION, ... (7 entities in total) |
Functional Keywords | ssgcid, structural genomics, seattle structural genomics center for infectious disease, dihydrofolate reductase, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase, oxidoreductase-inhibitor complex, oxidoreductase/inhibitor |
Biological source | Mycobacterium ulcerans |
Total number of polymer chains | 1 |
Total formula weight | 20664.01 |
Authors | Seattle Structural Genomics Center for Infectious Disease,Seattle Structural Genomics Center for Infectious Disease (SSGCID) (deposition date: 2023-06-26, release date: 2024-08-28) |
Primary citation | Woodward, E.L.,Lovell, S.,Mian, M.R.,Seibold, S. Crystal Structure of Dihydrofolate reductase (DHFR) from Mycobacterium ulcerans Agy99 in complex with NADP and inhibitor MAM907 To be published, |
Experimental method | X-RAY DIFFRACTION (1.5 Å) |
Structure validation
Download full validation report