8T8N

Venezuelan Equine Encephalitis Virus (VEEV) Nonstructural Protein 2 (nsP2) Cysteine Protease Inhibited with CA074

Summary for 8T8N

Entry DOI	10.2210/pdb8t8n/pdb
Related	5EZS
Related PRD ID	PRD_001032
Descriptor	Protease nsP2, [PROPYLAMINO-3-HYDROXY-BUTAN-1,4-DIONYL]-ISOLEUCYL-PROLINE (3 entities in total)
Functional Keywords	cysteine protease, ca074, alphavirus, covalent, inhibitor, viral protein
Biological source	Venezuelan equine encephalitis virus
Total number of polymer chains	1
Total formula weight	38727.25
Authors	Compton, J.R.,Legler, P.M. (deposition date: 2023-06-22, release date: 2023-08-09)
Primary citation	Hu, X.,Morazzani, E.,Compton, J.R.,Harmon, M.,Soloveva, V.,Glass, P.J.,Garcia, A.D.,Marugan, J.J.,Legler, P.M. In Silico Screening of Inhibitors of the Venezuelan Equine Encephalitis Virus Nonstructural Protein 2 Cysteine Protease. Viruses, 15:-, 2023 Cited by PubMed: 37515189 DOI: 10.3390/v15071503 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.32 Å)

Structure validation