8T88

FphE, Staphylococcus aureus fluorophosphonate-binding serine hydrolases E, Oxadiazolone JJ004 bound

8T88 の概要

• エントリーDOI: 10.2210/pdb8t88/pdb
• 分子名称: Fluorophosphonate-binding serine hydrolase E, methyl 2-formyl-2-[4-(undec-10-ynamido)phenyl]hydrazine-1-carboxylate, MAGNESIUM ION, ... (4 entities in total)
• 機能のキーワード: fphe, staphylococcus aureus, s. aureus, fluorophosphonate-binding, serine hydrolases, lipase, hydrolase
• 由来する生物種: Staphylococcus aureus USA300-0114
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 63345.70

構造登録者

Fellner, M. (登録日: 2023-06-22, 公開日: 2024-03-06, 最終更新日: 2024-03-27)

• 主引用文献: Jo, J.,Upadhyay, T.,Woods, E.C.,Park, K.W.,Pedowitz, N.J.,Jaworek-Korjakowska, J.,Wang, S.,Valdez, T.A.,Fellner, M.,Bogyo, M.; Development of Oxadiazolone Activity-Based Probes Targeting FphE for Specific Detection of Staphylococcus aureus Infections.; J.Am.Chem.Soc., 146:6880-6892, 2024; PubMed: 38411555; DOI: 10.1021/jacs.3c13974

実験手法

X-RAY DIFFRACTION (1.54 Å)