8T6V
Cryo-EM structure of human Anion Exchanger 1 bound to 4,4'-Diisothiocyanatostilbene-2,2'-Disulfonic Acid (DIDS)
Summary for 8T6V
Entry DOI | 10.2210/pdb8t6v/pdb |
EMDB information | 41082 |
Descriptor | Band 3 anion transport protein, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4,4'-Diisothiocyano-2,2'-stilbenedisulfonic acid, ... (7 entities in total) |
Functional Keywords | transmembrane, transport protein |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 123139.72 |
Authors | Capper, M.J.,Zilberg, G.,Mathiharan, Y.K.,Yang, S.,Stone, A.C.,Wacker, D. (deposition date: 2023-06-18, release date: 2023-09-13, Last modification date: 2023-11-01) |
Primary citation | Capper, M.J.,Yang, S.,Stone, A.C.,Vatansever, S.,Zilberg, G.,Mathiharan, Y.K.,Habib, R.,Hutchinson, K.,Zhao, Y.,Schlessinger, A.,Mezei, M.,Osman, R.,Zhang, B.,Wacker, D. Substrate binding and inhibition of the anion exchanger 1 transporter. Nat.Struct.Mol.Biol., 30:1495-1504, 2023 Cited by PubMed: 37679563DOI: 10.1038/s41594-023-01085-6 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.95 Å) |
Structure validation
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