8T6V

Cryo-EM structure of human Anion Exchanger 1 bound to 4,4'-Diisothiocyanatostilbene-2,2'-Disulfonic Acid (DIDS)

8T6V の概要

• エントリーDOI: 10.2210/pdb8t6v/pdb
• EMDBエントリー: 41082
• 分子名称: Band 3 anion transport protein, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4,4'-Diisothiocyano-2,2'-stilbenedisulfonic acid, ... (7 entities in total)
• 機能のキーワード: transmembrane, transport protein
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 123139.72

構造登録者

Capper, M.J.,Zilberg, G.,Mathiharan, Y.K.,Yang, S.,Stone, A.C.,Wacker, D. (登録日: 2023-06-18, 公開日: 2023-09-13, 最終更新日: 2023-11-01)

• 主引用文献: Capper, M.J.,Yang, S.,Stone, A.C.,Vatansever, S.,Zilberg, G.,Mathiharan, Y.K.,Habib, R.,Hutchinson, K.,Zhao, Y.,Schlessinger, A.,Mezei, M.,Osman, R.,Zhang, B.,Wacker, D.; Substrate binding and inhibition of the anion exchanger 1 transporter.; Nat.Struct.Mol.Biol., 30:1495-1504, 2023; PubMed: 37679563; DOI: 10.1038/s41594-023-01085-6

実験手法

ELECTRON MICROSCOPY (2.95 Å)