8T6J

CDPPB-bound inactive mGlu5

Summary for 8T6J

Entry DOI	10.2210/pdb8t6j/pdb
EMDB information	41069 41783 41787
Descriptor	Metabotropic glutamate receptor 5, 3-cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide (2 entities in total)
Functional Keywords	gpcr, signaling protein
Biological source	Homo sapiens (human)
Total number of polymer chains	2
Total formula weight	198465.39
Authors	Krishna Kumar, K.,Wang, H.,Kobilka, B.K. (deposition date: 2023-06-16, release date: 2023-10-11, Last modification date: 2024-06-05)
Primary citation	Krishna Kumar, K.,Wang, H.,Habrian, C.,Latorraca, N.R.,Xu, J.,O'Brien, E.S.,Zhang, C.,Montabana, E.,Koehl, A.,Marqusee, S.,Isacoff, E.Y.,Kobilka, B.K. Stepwise activation of a metabotropic glutamate receptor. Nature, 629:951-956, 2024 Cited by PubMed: 38632403 DOI: 10.1038/s41586-024-07327-x PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.5 Å)

Structure validation