8T23

Cryo-EM structure of the RBD-ACE2 interface of the SARS-CoV-2 trimeric spike protein bound to ACE2 receptor after local refinement at upRBD conformation

8T23 の概要

• エントリーDOI: 10.2210/pdb8t23/pdb
• EMDBエントリー: 40979
• 分子名称: Angiotensin-converting enzyme, Spike glycoprotein, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• 機能のキーワード: coronavirus, spike, ace2, mink, protein binding, viral protein
• 由来する生物種: Neovison vison; 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 113979.91

構造登録者

Ahn, H.M.,Calderon, B.,Fan, X.,Gao, Y.,Horgan, N.,Zhou, B.,Liang, B. (登録日: 2023-06-05, 公開日: 2023-10-25)

• 主引用文献: Ahn, H.,Calderon, B.M.,Fan, X.,Gao, Y.,Horgan, N.L.,Jiang, N.,Blohm, D.S.,Hossain, J.,Rayyan, N.W.K.,Osman, S.H.,Lin, X.,Currier, M.,Steel, J.,Wentworth, D.E.,Zhou, B.,Liang, B.; Structural basis of the American mink ACE2 binding by Y453F trimeric spike glycoproteins of SARS-CoV-2.; J Med Virol, 95:e29163-e29163, 2023; PubMed: 37842796; DOI: 10.1002/jmv.29163

実験手法

ELECTRON MICROSCOPY (3.87 Å)