8T0E

TRPV1 in Nanodisc not bound with lysophosphatidic acid (apo)

Summary for 8T0E

• Entry DOI: 10.2210/pdb8t0e/pdb
• EMDB information: 40941
• Descriptor: Transient receptor potential cation channel subfamily V member 1, (2R)-3-{[(R)-hydroxy{[(1S,2R,3R,4S,5S,6R)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dioctadecanoate, SODIUM ION, ... (4 entities in total)
• Functional Keywords: trpv1, lysophosphatidic acid, membrane protein
• Biological source: Rattus norvegicus (Norway rat)
• Total number of polymer chains: 4
• Total formula weight: 374108.23

Authors

Arnold, W.R.,Cheng, Y. (deposition date: 2023-05-31, release date: 2024-05-08, Last modification date: 2024-05-15)

• Primary citation: Arnold, W.R.,Mancino, A.,Moss 3rd, F.R.,Frost, A.,Julius, D.,Cheng, Y.; Structural basis of TRPV1 modulation by endogenous bioactive lipids.; Nat.Struct.Mol.Biol., 2024; PubMed: 38698206; DOI: 10.1038/s41594-024-01299-2

Experimental method

ELECTRON MICROSCOPY (3.3 Å)