8SY7

E. coli DNA-directed RNA polymerase transcription elongation complex bound the unnatural dB-STP base pair in the active site

8SY7 の概要

• エントリーDOI: 10.2210/pdb8sy7/pdb
• EMDBエントリー: 40864
• 分子名称: DNA-directed RNA polymerase subunit alpha, [[(2~{R},3~{S},4~{R},5~{S})-5-(4-azanyl-1-methyl-2-oxidanylidene-pyrimidin-5-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate, DNA-directed RNA polymerase subunit beta, ... (11 entities in total)
• 機能のキーワード: complex, unnatural base pairs, synthetic biology, transcription, transcription-dna-rna complex, transcription/dna/rna
• 由来する生物種: Escherichia coli; 詳細
• タンパク質・核酸の鎖数: 8
• 化学式量合計: 410283.88

構造登録者

Shan, Z.,Lyumkis, D.,Oh, J.,Wang, D. (登録日: 2023-05-24, 公開日: 2023-12-27)

• 主引用文献: Oh, J.,Shan, Z.,Hoshika, S.,Xu, J.,Chong, J.,Benner, S.A.,Lyumkis, D.,Wang, D.; A unified Watson-Crick geometry drives transcription of six-letter expanded DNA alphabets by E. coli RNA polymerase.; Nat Commun, 14:8219-8219, 2023; PubMed: 38086811; DOI: 10.1038/s41467-023-43735-9

実験手法