8SXP
Crystal structure of long neurotoxin from the venom of the king cobra (3FTx-L15) in complex with Fab of broadly neutralizing antibody 95Mat5
Summary for 8SXP
Entry DOI | 10.2210/pdb8sxp/pdb |
Descriptor | 95Mat5 Fab light chain, Long neurotoxin 2, 95Mat5 Fab heavy chain, ... (4 entities in total) |
Functional Keywords | snake toxin, antibody, toxin, toxin-immune system complex, toxin/immune system |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 3 |
Total formula weight | 54709.01 |
Authors | |
Primary citation | Khalek, I.S.,Senji Laxme, R.R.,Nguyen, Y.T.K.,Khochare, S.,Patel, R.N.,Woehl, J.,Smith, J.M.,Saye-Francisco, K.,Kim, Y.,Misson Mindrebo, L.,Tran, Q.,Kedzior, M.,Bore, E.,Limbo, O.,Verma, M.,Stanfield, R.L.,Menzies, S.K.,Ainsworth, S.,Harrison, R.A.,Burton, D.R.,Sok, D.,Wilson, I.A.,Casewell, N.R.,Sunagar, K.,Jardine, J.G. Synthetic development of a broadly neutralizing antibody against snake venom long-chain neurotoxins Sci Transl Med, 16:eadk1867-, 2024 Cited by PubMed: 38381847DOI: 10.1126/scitranslmed.adk1867 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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