8SXP

Crystal structure of long neurotoxin from the venom of the king cobra (3FTx-L15) in complex with Fab of broadly neutralizing antibody 95Mat5

8SXP の概要

• エントリーDOI: 10.2210/pdb8sxp/pdb
• 分子名称: 95Mat5 Fab light chain, Long neurotoxin 2, 95Mat5 Fab heavy chain, ... (4 entities in total)
• 機能のキーワード: snake toxin, antibody, toxin, toxin-immune system complex, toxin/immune system
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 54709.01

構造登録者

Nguyen, T.K.Y. (登録日: 2023-05-23, 公開日: 2024-03-20)

• 主引用文献: Khalek, I.S.,Senji Laxme, R.R.,Nguyen, Y.T.K.,Khochare, S.,Patel, R.N.,Woehl, J.,Smith, J.M.,Saye-Francisco, K.,Kim, Y.,Misson Mindrebo, L.,Tran, Q.,Kedzior, M.,Bore, E.,Limbo, O.,Verma, M.,Stanfield, R.L.,Menzies, S.K.,Ainsworth, S.,Harrison, R.A.,Burton, D.R.,Sok, D.,Wilson, I.A.,Casewell, N.R.,Sunagar, K.,Jardine, J.G.; Synthetic development of a broadly neutralizing antibody against snake venom long-chain neurotoxins; Sci Transl Med, 16:eadk1867-, 2024; PubMed: 38381847; DOI: 10.1126/scitranslmed.adk1867

実験手法

X-RAY DIFFRACTION (2.9 Å)