8SWP

Structure of K. lactis PNP bound to hypoxanthine

Summary for 8SWP

Entry DOI	10.2210/pdb8swp/pdb
Descriptor	Purine nucleoside phosphorylase, HYPOXANTHINE, ACETATE ION, ... (4 entities in total)
Functional Keywords	pentosyltransferase, purine nucleoside phosphorylase, transferase
Biological source	Kluyveromyces lactis NRRL Y-1140
Total number of polymer chains	6
Total formula weight	203158.32
Authors	Fedorov, E.,Ghosh, A. (deposition date: 2023-05-19, release date: 2023-10-18, Last modification date: 2023-11-22)
Primary citation	Minnow, Y.V.T.,Schramm, V.L.,Almo, S.C.,Ghosh, A. Phosphate Binding in PNP Alters Transition-State Analogue Affinity and Subunit Cooperativity. Biochemistry, 62:3116-3125, 2023 Cited by PubMed: 37812583 DOI: 10.1021/acs.biochem.3c00264 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation